PSMD9 Antibody

CATALOG NUMBER: 57-798

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PSMD9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-205 amino acids from the C-terminal region of human PSMD9.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
25 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PSMD9
Additional Names:
26S proteasome non-ATPase regulatory subunit 9, 26S proteasome regulatory subunit p27, PSMD9
Protein Accession Number:
O00233
Ncbi Gene Id Number:
5715
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The 26S proteasome is a multicatalytic proteinase complexwith a highly ordered structure composed of 2 complexes, a 20S coreand a 19S regulator. The 20S core is composed of 4 rings of 28non-identical subunits; 2 rings are composed of 7 alpha subunitsand 2 rings are composed of 7 beta subunits. The 19S regulator iscomposed of a base, which contains 6 ATPase subunits and 2non-ATPase subunits, and a lid, which contains up to 10 non-ATPasesubunits. Proteasomes are distributed throughout eukaryotic cellsat a high concentration and cleave peptides in anATP/ubiquitin-dependent process in a non-lysosomal pathway. Anessential function of a modified proteasome, the immunoproteasome,is the processing of class I MHC peptides. This gene encodes anon-ATPase subunit of the 19S regulator.
Background Reference 1:
Gragnoli, C. J. Cell. Physiol. 223(1):1-5(2010)
Background Reference 2:
Huang, L.W., et al. Pathol. Oncol. Res. 16(1):81-86(2010)
Background Reference 3:
Gragnoli, C. J. Cell. Physiol. 222(2):265-267(2010)
Background Reference 4:
Kaneko, T., et al. Cell 137(5):914-925(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-798

List Size:
400 ul

List Price:

$495.00

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