PTAFR Antibody

CATALOG NUMBER: 61-919

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PTAFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-312 amino acids from the C-terminal region of human PTAFR.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
39 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PTAFR
Additional Names:
Platelet-activating factor receptor, PAF-R, PAFr, PTAFR, PAFR
Protein Accession Number:
P25105
Protein Gi Number:
129557
Ncbi Gene Id Number:
5724
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
PTAFR shows structural characteristics of the rhodopsin(MIM 180380) gene family and binds platelet-activating factor(PAF). PAF is a phospholipid(1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has beenimplicated as a mediator in diverse pathologic processes, such asallergy, asthma, septic shock, arterial thrombosis, andinflammatory processes.
Background Reference 1:
Davila, S., et al. Genes Immun. (2010) In press :
Background Reference 2:
Hirota, N., et al. J. Biol. Chem. 285(8):5931-5940(2010)
Background Reference 3:
Kaneko, K., et al. J. Invest. Dermatol. 129(11):2567-2573(2009)
Background Reference 4:
Melnikova, V.O., et al. J. Biol. Chem. 284(42):28845-28855(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-919

List Size:
400 ul

List Price:

$495.00

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