PTCH1 Antibody

CATALOG NUMBER: 29-972

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PTCH1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
PTCH1 antibody can be used for detection of PTCH1 by ELISA at 1:312500. PTCH1 antibody can be used for detection of PTCH1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
37 kDa, 161 kDa, 154 kDa, 161 kDa, 144 kDa, 144 kDa, 144 kDa, 144 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store PTCH1 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
PTCH1
Additional Names:
PTCH1, PTC, BCNS, HPE7, PTC1, PTCH, NBCCS, PTCH11
Protein Accession Number:
AAR21240
Protein Gi Number:
38489136
Ncbi Gene Id Number:
5727
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
PTCH1 is a member of the patched gene family. The protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis. It functions as a tumor suppressor. Mutations of its gene have been associated with nevoid basal cell carcinoma syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

29-972

List Size:
100 ul

List Price:

$519.00

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