PTCRA Antibody

CATALOG NUMBER: 60-241

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PTCRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-225 amino acids from the C-terminal region of human PTCRA.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
29 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PTCRA
Additional Names:
Pre T-cell antigen receptor alpha, pT-alpha, pTa, pT-alpha-TCR, PTCRA
Protein Accession Number:
Q6ISU1
Protein Gi Number:
74736631
Ncbi Gene Id Number:
171558
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
In immature T cells the T-cell receptor beta-chain gene(TCRB; MIM 186930) is rearranged and expressed before the TCRA (MIM186880) chain. At this early stage, TCRB can associate with thepre-T-cell receptor alpha chain (PTCRA). The PTCRA, together withTCRB and the CD3 complex (see MIM 186740), minimally make up thepre-T cell receptor (pre-TCR), which regulates early T celldevelopment.
Background Reference 1:
Velez, D.R., et al. Am. J. Obstet. Gynecol. 200 (2), 209 (2009) :
Background Reference 2:
Menon, R., et al. Reprod. Biol. Endocrinol. 7, 62 (2009) :
Background Reference 3:
Velez, D.R., et al. PLoS ONE(9), E3283 (2008) :
Background Reference 4:
Navarro, M.N., et al. Blood 110(13):4331-4340(2007)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-241

List Size:
400 ul

List Price:

$495.00

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