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Western blot analysis of PTER in human kidney tissue lysate with PTER antibody at (A) 1 and (B) 2 μg/mL.
Immunohistochemistry of PTER in mouse kidney tissue with PTER antibody at 2.5 μg/mL.
Western blot analysis of PTER in human kidney tissue lysate with PTER antibody at (A) 1 and (B) 2 μg/mL.
Trial Size

PTER Antibody

CATALOG NUMBER: 5173

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (88%)
Immunogen:
PTER antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human PTER.
The immunogen is located within amino acids 250 - 300 of PTER.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC-P, WB
Application Note:
PTER antibody can be used for detection of PTER by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
Positive Control 1:
Cat. No. 1305 - Human Kidney Tissue Lysate
Purification:
PTER Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
PTER Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
PTER antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PTER
Additional Names:
PTER Antibody: HPHRP, RPR-1, Phosphotriesterase-related protein, Parathion hydrolase-related protein, hPHRP
Protein Accession Number:
CAH73146
Protein Gi Number:
55664514
Ncbi Gene Id Number:
9317
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
PTER Antibody: PTER is a mammalian homolog to bacterial phosphotriesterases, enzymes that hydrolyze phosphotriester-containing organophosphate pesticides. It is expressed primarily in the proximal renal tubules and the gene has been localized in humans to chromosomal band 10p12 by in situ hybridization. PTER, in addition to FTO, MC4R, and NPC1 has recently been shown to be a new risk loci for early-onset and morbid adult obesity in European populations. At least two isoforms of PTER are known to exist.
Background Reference 1:
Davies JA, Buchman VL, Krylova O, et al. Molecular cloning and expression pattern of rpr-1, a resiniferatoxin-binding, phosphotriesterase-related protein, expressed in rat kidney tubules. FEBS Lett.1997; 410:378-82.
Background Reference 2:
Alimova-Kost MV, Imreh S, Buchman VL, et al. Assignment of phosphotriesterase-related gene (PTER) to human chromosome band 10p12 by in situ hybridization. Cytogenet.. Cell Genet.1998; 83:16-7.
Background Reference 3:
Meyre D, Delplanque J, Chevre JC, et al. Genome-wide associated study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat. Genet.2009; 41:157-9.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

5173

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
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