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Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis in K562 cell line lysates (35ug/lane).

PTF1A Antibody

CATALOG NUMBER: 57-324

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PTF1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-316 amino acids from the C-terminal region of human PTF1A.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
35 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PTF1A
Additional Names:
Pancreas transcription factor 1 subunit alpha, Class A basic helix-loop-helix protein 29, bHLHa29, Pancreas-specific transcription factor 1a, bHLH transcription factor p48, p48 DNA-binding subunit of transcription factor PTF1, PTF1-p48, PTF1A, BHLHA29, PTF1P48
Protein Accession Number:
Q7RTS3
Protein Gi Number:
74749931
Ncbi Gene Id Number:
256297
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein that is a component of thepancreas transcription factor 1 complex (PTF1) and is known to havea role in mammalian pancreatic development. The protein plays arole in determining whether cells allocated to the pancreatic budscontinue towards pancreatic organogenesis or revert back toduodenal fates. The protein is thought to be involved in themaintenance of exocrine pancreas-specific gene expression includingelastase 1 and amylase. Mutations in this gene cause cerebellaragenesis and loss of expression is seen in ductal type pancreascancers.
Background Reference 1:
Meredith, D.M., et al. J. Neurosci. 29(36):11139-11148(2009)
Background Reference 2:
Rodolosse, A., et al. Biochem. J. 418(2):463-473(2009)
Background Reference 3:
Tutak, E., et al. Genet. Couns. 20(2):147-152(2009)
Background Reference 4:
Yamada, M., et al. J. Neurosci. 27(41):10924-10934(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-324

List Size:
400 ul

List Price:

$495.00

Datasheet
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