PTP4A1 Antibody

CATALOG NUMBER: 58-807

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Rat
Immunogen:
This PTP4A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the C-terminal region of human PTP4A1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
20 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PTP4A1
Additional Names:
Protein tyrosine phosphatase type IVA 1, PTP(CAAXI), Protein-tyrosine phosphatase 4a1, Protein-tyrosine phosphatase of regenerating liver 1, PRL-1, PTP4A1, PRL1, PTPCAAX1
Protein Accession Number:
Q93096
Protein Gi Number:
68566217
Ncbi Gene Id Number:
7803
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene belongs to a small classof prenylated protein tyrosine phosphatases (PTPs), which containsa PTP domain and a characteristic C-terminal prenylation motif.PTPs are cell signaling molecules that play regulatory roles in avariety of cellular processes. This tyrosine phosphatase is anuclear protein, but may primarily associate with plasma membrane.The surface membrane association of this protein depends on itsC-terminal prenylation. Overexpression of this gene in mammaliancells conferred a transformed phenotype, which implicated its rolein the tumorigenesis. Studies in rat suggested that this gene maybe an immediate-early gene in mitogen-stimulated cells. [providedby RefSeq].
Background Reference 1:
Johnatty, S.E., et al. PLoS Genet.(7), E1001016 (2010) :
Background Reference 2:
Skinner, A.L., et al. Biochemistry 48(20):4262-4272(2009)
Background Reference 3:
Luo, Y., et al. Biochemistry 48(8):1838-1846(2009)
Background Reference 4:
Min, S.H., et al. Oncogene 28(4):545-554(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-807

List Size:
400 ul

List Price:

$495.00

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