PTPN1 Antibody

CATALOG NUMBER: XW-7826

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Chicken
Species Reactivity:
Human, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human, Rat
Immunogen:
288-364
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Tyrosine-protein phosphatase non-receptor type 1 antibody can be used for the detection of Tyrosine-protein phosphatase non-receptor type 1 by Western Blot.
Predicted Molecular Weight:
50 kDa (calculated)
Purification:
Immunoaffinity Purified
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
PTPN1 antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PTPN1
Additional Names:
PTP1B, Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine phosphatase 1B, PTP-1B, PTP1B, Tyrosineprotein phosphatase nonreceptor type 1
Protein Accession Number:
NP_002818.1
Protein Gi Number:
4506289
Ncbi Gene Id Number:
5770
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
FUNCTION: May play an important role in CKII- and p60c-src-induced signal transduction cascades (By similarity).

CATALYTIC ACTIVITY: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

PTM: Oxidized on Cys-215; the Cys-SOH formed in response to redox signaling reacts with the α-amido of the following residue to form a 4-amino-3-isothiazolidinone serine cross-link, triggering a conformational change that inhibits substrate binding and activity. The active site can be restored by reduction.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7826

List Size:
0.05 mg

List Price:

$638.00

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