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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Western blot analysis of PTPN18 using rabbit polyclonal PTPN18 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PTPN18 gene.
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

PTPN18 Antibody

CATALOG NUMBER: 58-809

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This PTPN18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 430-459 amino acids from the C-terminal region of human PTPN18.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
50 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PTPN18
Additional Names:
Tyrosine-protein phosphatase non-receptor type 18, Brain-derived phosphatase, PTPN18, BDP1
Protein Accession Number:
Q99952
Protein Gi Number:
215273871
Ncbi Gene Id Number:
26469
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of theprotein tyrosine phosphatase (PTP) family. PTPs are known to besignaling molecules that regulate a variety of cellular processesincluding cell growth, differentiation, the mitotic cycle, andoncogenic transformation. This PTP contains a PEST motif, whichoften serves as a protein-protein interaction domain, and may berelated to protein intracellular half-live. This protein candifferentially dephosphorylate autophosphorylated tyrosine kinasesthat are overexpressed in tumor tissues, and it appears to regulateHER2, a member of the epidermal growth factor receptor family ofreceptor tyrosine kinases. Two transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
Background Reference 1:
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Background Reference 2:
Zhang, Y., et al. Mol. Cell Proteomics 4(9):1240-1250(2005)
Background Reference 3:
Tao, W.A., et al. Nat. Methods 2(8):591-598(2005)
Background Reference 4:
Blanchetot, C., et al. Methods 35(1):44-53(2005)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-809

List Size:
400 ul

List Price:

$495.00

Datasheet
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