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Western blot analysis of anti-PTPN7 Antibody (S44) in Jurkat cell line lysates (35ug/lane)
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PTPN7 Antibody (S44) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Western blot analysis of anti-PTPN7 Antibody (S44) in Jurkat cell line lysates (35ug/lane)

PTPN7 Antibody

CATALOG NUMBER: 63-024

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PTPN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-51 amino acids from human PTPN7.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
41 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PTPN7
Additional Names:
Tyrosine-protein phosphatase non-receptor type 7, Hematopoietic protein-tyrosine phosphatase, HEPTP, Protein-tyrosine phosphatase LC-PTP, PTPN7
Protein Accession Number:
P35236
Protein Gi Number:
20141721
Ncbi Gene Id Number:
5778
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
PTPN7 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN7 is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP has been shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which is thought to function through dephosphorylating the molecules related to MAP kinase pathway.
Background Reference 1:
Eswaran,J., Biochem. J. 395 (3), 483-491 (2006)
Background Reference 2:
Mustelin,T., J. Mol. Biol. 354 (1), 150-163 (2005)
Background Reference 3:
Pettiford,S.M., Leukemia 17 (2), 366-378 (2003)
Background Reference 4:
Kosaki,K., J. Clin. Endocrinol. Metab. 87 (8), 3529-3533 (2002)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

63-024

List Size:
400 ul

List Price:

$495.00

Datasheet
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