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Western blot analysis in CEM cell line lysates (35ug/lane).
PTPRE Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in CEM cell line lysates (35ug/lane).

PTPRE Antibody

CATALOG NUMBER: 57-711

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This PTPRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from the N-terminal region of human PTPRE.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
81 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PTPRE
Additional Names:
Receptor-type tyrosine-protein phosphatase epsilon, Protein-tyrosine phosphatase epsilon, R-PTP-epsilon, PTPRE
Protein Accession Number:
P23469
Protein Gi Number:
126471
Ncbi Gene Id Number:
5791
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of theprotein tyrosine phosphatase (PTP) family. PTPs are known to besignaling molecules that regulate a variety of cellular processesincluding cell growth, differentiation, mitotic cycle, andoncogenic transformation. Two alternatively spliced transcriptvariants of this gene have been reported, one of which encodes areceptor-type PTP that possesses a short extracellular domain, asingle transmembrane region, and two tandem intracytoplasmiccatalytic domains; Another one encodes a PTP that contains adistinct hydrophilic N-terminus, and thus represents anonreceptor-type isoform of this PTP. Studies of the similar genein mice suggested the regulatory roles of this PTP in RAS relatedsignal transduction pathways, cytokines induced SATA signaling, aswell as the activation of voltage-gated K+ channels. [provided byRefSeq].
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Background Reference 3:
Barr, A.J., et al. Cell 136(2):352-363(2009)
Background Reference 4:
Kraut-Cohen, J., et al. J. Biol. Chem. 283(8):4612-4621(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-711

List Size:
400 ul

List Price:

$495.00

Datasheet
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