PTPRG Antibody

CATALOG NUMBER: 58-007

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This PTPRG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 671-700 amino acids from the Central region of human PTPRG.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
162 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PTPRG
Additional Names:
Receptor-type tyrosine-protein phosphatase gamma, Protein-tyrosine phosphatase gamma, R-PTP-gamma, PTPRG, PTPG
Protein Accession Number:
P23470
Protein Gi Number:
229463033
Ncbi Gene Id Number:
5793
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of theprotein tyrosine phosphatase (PTP) family. PTPs are known to besignaling molecules that regulate a variety of cellular processesincluding cell growth, differentiation, mitotic cycle, andoncogenic transformation. This PTP possesses an extracellularregion, a single transmembrane region, and two tandemintracytoplasmic catalytic domains, and thus represents areceptor-type PTP. The extracellular region of this PTP contains acarbonic anhydrase-like (CAH) domain, which is also found in theextracellular region of PTPRBETA/ZETA. This gene is located in achromosomal region that is frequently deleted in renal cellcarcinoma and lung carcinoma, thus is thought to be a candidatetumor suppressor gene.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Shu, S.T., et al. Anticancer Res. 30(6):1937-1946(2010)
Background Reference 3:
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Background Reference 4:
Bouyain, S., et al. Proc. Natl. Acad. Sci. U.S.A. 107(6):2443-2448(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-007

List Size:
400 ul

List Price:

$495.00

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