PTPRJ Antibody

CATALOG NUMBER: XW-7820

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Chicken
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human
Immunogen:
206-292
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Protein-tyrosine phosphatase antibody can be used for the detection of Protein-tyrosine phosphatase by Western Blot.
Predicted Molecular Weight:
14.3 kDa (calculated)
Purification:
Immunoaffinity Purified
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
PTPRJ antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PTPRJ
Additional Names:
DEP1, Receptor-type tyrosine-protein phosphatase eta, Density-enhanced phosphatase 1, Protein-tyrosine phosphatase eta, DEP1, SCC1, CD148, HPTPeta, R-PTP-ETA, Proteintyrosine phosphatase
Protein Accession Number:
NP_002834.2
Protein Gi Number:
18860900
Ncbi Gene Id Number:
5795
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This PTP is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C γ 1 (PLCG1) and Linker for Activation of T Cells (LAT). This PTP was also found to dephosphorylate PDGF β receptor, and may be involved in UV-induced signal transduction.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7820

List Size:
0.05 mg

List Price:

$565.00

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