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Western blot analysis in Jurkat cell line lysates (35ug/lane).
Western blot analysis in Jurkat cell line lysates (35ug/lane).

PTPRN Antibody

CATALOG NUMBER: 57-787

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PTPRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-316 amino acids from the Central region of human PTPRN.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
106 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PTPRN
Additional Names:
Receptor-type tyrosine-protein phosphatase-like N, R-PTP-N, Islet cell antigen 512, ICA 512, Islet cell autoantigen 3, PTP IA-2, PTPRN, ICA3, ICA512
Protein Accession Number:
Q16849
Protein Gi Number:
2499754
Ncbi Gene Id Number:
5798
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of theprotein tyrosine phosphatase (PTP) family. PTPs are known to besignaling molecules that regulate a variety of cellular processesincluding cell growth, differentiation, mitotic cycle, andoncogenic transformation. This PTP possesses an extracellularregion, a single transmembrane region, and a single catalyticdomain, and thus represents a receptor-type PTP. This PTP was foundto be an autoantigen that is reactive with insulin-dependentdiabetes mellitus (IDDM) patient sera, and thus may be a potentialtarget of autoimmunity in diabetes mellitus.
Background Reference 1:
Yu, L., et al. J. Immunol. Methods 353 (1-2), 20-23 (2010) :
Background Reference 2:
Honeyman, M.C., et al. J. Immunol. 184(4):2204-2210(2010)
Background Reference 3:
Weenink, S.M., et al. J. Autoimmun. 33(2):147-154(2009)
Background Reference 4:
Burbelo, P.D., et al. Diabetes Care 31(9):1824-1826(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-787

List Size:
400 ul

List Price:

$495.00

Datasheet
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