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Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis in K562 cell line lysates (35ug/lane).

PVR Antibody

CATALOG NUMBER: 60-818

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PVR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-342 amino acids from the C-terminal region of human PVR.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
45 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PVR
Additional Names:
Poliovirus receptor, Nectin-like protein 5, NECL-5, CD155, PVR, PVS
Protein Accession Number:
P15151
Protein Gi Number:
1346922
Ncbi Gene Id Number:
5817
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a transmembraneglycoprotein belonging to the immunoglobulin superfamily. Theexternal domain mediates cell attachment to the extracellularmatrix molecule vitronectin, while its intracellular domaininteracts with the dynein light chain Tctex-1/DYNLT1. The gene isspecific to the primate lineage, and serves as a cellular receptorfor poliovirus in the first step of poliovirus replication.Multiple transcript variants encoding different isoforms have beenfound for this gene.
Background Reference 1:
Nakai, R., et al. Cancer Sci. 101(5):1326-1330(2010)
Background Reference 2:
Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
Background Reference 3:
Stanietsky, N., et al. Proc. Natl. Acad. Sci. U.S.A. 106(42):17858-17863(2009)
Background Reference 4:
Carlsten, M., et al. J. Immunol. 183(8):4921-4930(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-818

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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