PVRL3 Antibody

CATALOG NUMBER: 56-704

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PVRL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 507-536 amino acids from the C-terminal region of human PVRL3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
61 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PVRL3
Additional Names:
Nectin-3, CDw113, Poliovirus receptor-related protein 3, CD113, PVRL3, PRR3
Protein Accession Number:
Q9NQS3
Protein Gi Number:
74762752
Ncbi Gene Id Number:
25945
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Nectins (e.g., PVRL1; MIM 600644) are immunoglobulin-likeadhesion molecules that interact with afadin (AF6; MIM 159559).Afadin is an actin filament-binding protein that connects nectinsto the actin cytoskeleton. The nectin-afadin system organizesadherens junctions cooperatively with the cadherin (see MIM192090)-catenin (see MIM 116805) system in epithelialcells.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
Background Reference 3:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Background Reference 4:
Yu, X., et al. Nat. Immunol. 10(1):48-57(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-704

List Size:
400 ul

List Price:

$495.00

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