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Western blot analysis in human placenta tissue lysates (35ug/lane).
QPRT Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in human placenta tissue lysates (35ug/lane).

QPRT Antibody

CATALOG NUMBER: 57-694

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This QPRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the C-terminal region of human QPRT.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
31 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
QPRT
Additional Names:
Nicotinate-nucleotide pyrophosphorylase [carboxylating], Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase, QPRTase, QPRT
Protein Accession Number:
Q15274
Protein Gi Number:
296439291
Ncbi Gene Id Number:
23475
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a key enzyme in catabolism ofquinolinate, an intermediate in the tryptophan-nicotinamide adeninedinucleotide pathway. Quinolinate acts as a most potent endogenousexitotoxin to neurons. Elevation of quinolinate levels in the brainhas been linked to the pathogenesis of neurodegenerative disorderssuch as epilepsy, Alzheimer's disease, and Huntington's disease.
Background Reference 1:
Hinsch, N., et al. BMC Cancer 9, 93 (2009) :
Background Reference 2:
Liu, H., et al. J. Mol. Biol. 373(3):755-763(2007)
Background Reference 3:
Magni, G., et al. Cell. Mol. Life Sci. 61(1):19-34(2004)
Background Reference 4:
Fukuoka, S., et al. Adv. Exp. Med. Biol. 467, 611-614 (1999) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-694

List Size:
400 ul

List Price:

$495.00

Datasheet
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