RAC1 Antibody

CATALOG NUMBER: 63-008

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Rat
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, C. Elegans, Chicken, Drosophila, Monkey, Mouse, Pig
Immunogen:
This RAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-78 amino acids from human RAC1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:2000
Predicted Molecular Weight:
21 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RAC1
Additional Names:
Ras-related C3 botulinum toxin substrate 1, Cell migration-inducing gene 5 protein, Ras-like protein TC25, p21-Rac1, RAC1, TC25
Protein Accession Number:
P63000
Protein Gi Number:
51702787
Ncbi Gene Id Number:
5879
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
RAC1 is a GTPase belonging to the RAS superfamily of small GTP-binding proteins. It is a pleiotropic regulator of many cellular processes, including the cell cycle, cell-cell adhesion, motility (through the actin network), and of epithelial differentiation (proposed to be necessary for maintaining epidermal stem cells).
Background Reference 1:
Wang,T.,Neurosci. Lett. 437 (2), 71-75 (2008)
Background Reference 2:
Gorshkova,I., J. Biol. Chem. 283 (17), 11794-11806 (2008)
Background Reference 3:
Simeone-Penney,M.C.,Am. J. Physiol. Lung Cell Mol. Physiol. 294 (4), L698-L704 (2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

63-008

List Size:
400 ul

List Price:

$495.00

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