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Western blot analysis in HepG2 cell line lysates (35ug/lane).
Western blot analysis in HepG2 cell line lysates (35ug/lane).

RAD51C Antibody

CATALOG NUMBER: 58-132

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This RAD51C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-198 amino acids from the Central region of human RAD51C.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
42 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RAD51C
Additional Names:
DNA repair protein RAD51 homolog 3, R51H3, RAD51 homolog C, RAD51-like protein 2, RAD51C, RAD51L2
Protein Accession Number:
O43502
Ncbi Gene Id Number:
5889
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a member of the RAD51 family of relatedgenes, which encode strand-transfer proteins thought to be involvedin recombinational repair of damaged DNA and in meioticrecombination. This gene product interacts with two other DNArepair proteins, encoded by RAD51B and XRCC3, but not with itself.The protein copurifies with XRCC3 protein in a complex, reflectingtheir endogenous association and suggesting a cooperative roleduring recombinational repair. This gene is one of four localizedto a region of chromosome 17q23 where amplification occursfrequently in breast tumors. Overexpression of the four genesduring amplification has been observed and suggests a possible rolein tumor progression. Alternative splicing has been observed forthis gene and two variants encoding different isoforms have beenidentified.
Background Reference 1:
Zheng, Y., et al. Breast Cancer Res. Treat. (2010) In press :
Background Reference 2:
Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010)
Background Reference 3:
Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :
Background Reference 4:
Meindl, A., et al. Nat. Genet. 42(5):410-414(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-132

List Size:
400 ul

List Price:

$495.00

Datasheet
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