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Western Blot at 1:1000 dilution + mouse brain lysate Lysates/proteins at 20 ug per lane.
Western Blot at 1:2000 dilution + human lung lysate Lysates/proteins at 20 ug per lane.
Western Blot at 1:1000 dilution + mouse brain lysate Lysates/proteins at 20 ug per lane.

RAMP3 Antibody

CATALOG NUMBER: 58-214

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This RAMP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the C-terminal region of human RAMP3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
17 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RAMP3
Additional Names:
Receptor activity-modifying protein 3, Calcitonin-receptor-like receptor activity-modifying protein 3, CRLR activity-modifying protein 3, RAMP3
Protein Accession Number:
O60896
Ncbi Gene Id Number:
10268
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of the RAMPfamily of single-transmembrane-domain proteins, called receptor(calcitonin) activity modifying proteins (RAMPs). RAMPs are type Itransmembrane proteins with an extracellular N terminus and acytoplasmic C terminus. RAMPs are required to transportcalcitonin-receptor-like receptor (CRLR) to the plasma membrane.CRLR, a receptor with seven transmembrane domains, can function aseither a calcitonin-gene-related peptide (CGRP) receptor or anadrenomedullin receptor, depending on which members of the RAMPfamily are expressed. In the presence of this (RAMP3) protein, CRLRfunctions as an adrenomedullin receptor.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Bailey, R.J., et al. Peptides 31(4):579-584(2010)
Background Reference 3:
Harikumar, K.G., et al. Biochemistry 48(49):11773-11785(2009)
Background Reference 4:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-214

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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