RANBP17 Antibody

CATALOG NUMBER: 59-937

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This RANBP17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-175 amino acids from the N-terminal region of human RANBP17.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
124 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RANBP17
Additional Names:
Ran-binding protein 17, RANBP17
Protein Accession Number:
Q9H2T7
Protein Gi Number:
17368945
Ncbi Gene Id Number:
64901
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The transport of protein and large RNAs through thenuclear pore complexes (NPC) is an energy-dependent and regulatedprocess. The import of proteins with a nuclear localization signal(NLS) is accomplished by recognition of one or more clusters ofbasic amino acids by the importin-alpha/beta complex; see MIM600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays akey role in NLS-dependent protein import. RAN-binding protein-17 isa member of the importin-beta superfamily of nuclear transportreceptors.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Background Reference 3:
Kutay, U., et al. J. Biol. Chem. 275(51):40163-40168(2000)
Background Reference 4:
Koch, P., et al. Biochem. Biophys. Res. Commun. 278(1):241-249(2000)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-937

List Size:
400 ul

List Price:

$495.00

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