RARRES3 Antibody

CATALOG NUMBER: 60-161

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This RARRES3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-71 amino acids from the Central region of human RARRES3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
18 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RARRES3
Additional Names:
Retinoic acid receptor responder protein 3, 311-, HRAS-like suppressor 4, HRSL4, RAR-responsive protein TIG3, Retinoid-inducible gene 1 protein, Tazarotene-induced gene 3 protein, RARRES3, RIG1, TIG3
Protein Accession Number:
Q9UL19
Protein Gi Number:
20140910
Ncbi Gene Id Number:
5920
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Retinoids exert biologic effects such as potent growthinhibitory and cell differentiation activities and are used in thetreatment of hyperproliferative dermatological diseases. Theseeffects are mediated by specific nuclear receptor proteins that aremembers of the steroid and thyroid hormone receptor superfamily oftranscriptional regulators. RARRES1, RARRES2, and RARRES3 are geneswhose expression is upregulated by the synthetic retinoidtazarotene. RARRES3 is thought act as a tumor suppressor or growthregulator.
Background Reference 1:
Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)
Background Reference 2:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 3:
Uyama, T., et al. Biochim. Biophys. Acta 1791(12):1114-1124(2009)
Background Reference 4:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-161

List Size:
400 ul

List Price:

$495.00

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