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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

RASA3 Antibody

CATALOG NUMBER: 60-278

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This RASA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 594-623 amino acids from the C-terminal region of human RASA3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
96 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RASA3
Additional Names:
Ras GTPase-activating protein 3, GAP1(IP4BP), Ins P4-binding protein, RASA3
Protein Accession Number:
Q14644
Protein Gi Number:
206729910
Ncbi Gene Id Number:
22821
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is member of the GAP1family of GTPase-activating proteins. The gene product stimulatesthe GTPase activity of normal RAS p21 but not its oncogeniccounterpart. Acting as a suppressor of RAS function, the proteinenhances the weak intrinsic GTPase activity of RAS proteinsresulting in the inactive GDP-bound form of RAS, thereby allowingcontrol of cellular proliferation and differentiation. This familymember is an inositol 1,3,4,5-tetrakisphosphate-binding protein,like the closely related RAS p21 protein activator 2. The twofamily members have distinct pleckstrin-homology domains, with thisparticular member having a domain consistent with its localizationto the plasma membrane.
Background Reference 1:
Kupzig, S., et al. Mol. Cell. Biol. 29(14):3929-3940(2009)
Background Reference 2:
Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
Background Reference 3:
Walker, S.A., et al. J. Biol. Chem. 277(50):48779-48785(2002)
Background Reference 4:
Koehler, J.A., et al. Biochem. Biophys. Res. Commun. 283(4):888-895(2001)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-278

List Size:
400 ul

List Price:

$495.00

Datasheet
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