RBAK Antibody

CATALOG NUMBER: 58-617

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This RBAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the N-terminal region of human RBAK.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
83 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RBAK
Additional Names:
RB-associated KRAB zinc finger protein, RB-associated KRAB repressor, hRBaK, Zinc finger protein 769, RBAK, ZNF769
Protein Accession Number:
Q9NYW8
Protein Gi Number:
74761820
Ncbi Gene Id Number:
1.00534E+13
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a nuclear protein which interacts withthe tumor suppressor retinoblastoma 1. The two interacting proteinsare thought to act as a transcriptional repressor for promoterswhich are activated by the E2F1 transcription factor. This proteincontains a Kruppel-associated box (KRAB), which is atranscriptional repressor motif.
Background Reference 1:
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Background Reference 2:
Ma, Y., et al. BMC Genomics 10, 109 (2009) :
Background Reference 3:
Jeske, Y.W., et al. Clin. Exp. Pharmacol. Physiol. 35(4):380-385(2008)
Background Reference 4:
So, A., et al. Clin. Endocrinol. (Oxf) 65(6):829-831(2006)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-617

List Size:
400 ul

List Price:

$495.00

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