RBBP7 Antibody

CATALOG NUMBER: 58-401

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse, Rat
Immunogen:
This RBBP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the Central region of human RBBP7.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
48 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RBBP7
Additional Names:
Histone-binding protein RBBP7, Histone acetyltransferase type B subunit 2, Nucleosome-remodeling factor subunit RBAP46, Retinoblastoma-binding protein 7, RBBP-7, Retinoblastoma-binding protein p46, RBBP7, RBAP46
Protein Accession Number:
Q16576
Protein Gi Number:
2494891
Ncbi Gene Id Number:
5931
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This protein is a ubiquitously expressed nuclear proteinand belongs to a highly conserved subfamily of WD-repeat proteins.It is found among several proteins that binds directly toretinoblastoma protein, which regulates cell proliferation. Theencoded protein is found in many histone deacetylase complexes,including mSin3 co-repressor complex. It is also present in proteincomplexes involved in chromatin assembly. This protein can interactwith BRCA1 tumor-suppressor gene and may have a role in theregulation of cell proliferation and differentiation. Twotranscript variants encoding different isoforms have been found forthis gene.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Background Reference 3:
Saade, E., et al. Proteomics 9(21):4934-4943(2009)
Background Reference 4:
Wang, C.L., et al. J. Proteome Res. 8(10):4428-4440(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-401

List Size:
400 ul

List Price:

$495.00

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