RBM9 Antibody

CATALOG NUMBER: 29-264

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RBM9.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
RBM9 antibody can be used for detection of RBM9 by ELISA at 1:312500. RBM9 antibody can be used for detection of RBM9 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
40 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store RBM9 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
RBFOX2
Additional Names:
RBM9, Fox-2, HNRBP2, HRNBP2, RTA, dJ106I20.3, fxh, FOX2, RBM9
Protein Accession Number:
NP_001026865
Protein Gi Number:
72534682
Ncbi Gene Id Number:
23543
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
RBM9 is a RNA-binding protein that seems to act as a coregulatory factor of ER-alpha.This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.
Background Reference 1:
Yang, G., (2008) Blood 111 (1), 392-401.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

29-264

List Size:
100 ul

List Price:

$519.00

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