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Antibody used in WB on mouse osteoclasts at 1:1000.
Antibody used in WB on Mouse Brain at 1:500.
Antibody used in WB on Human Muscle at 0.2-1 ug/ml.
Antibody used in WB on Mouse left ventricle at 1:1000.
Antibody used in WB on mouse osteoclasts at 1:1000.

RCAN1 Antibody

CATALOG NUMBER: 25-434

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RCAN1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
RCAN1 antibody can be used for detection of RCAN1 by ELISA at 1:312500. RCAN1 antibody can be used for detection of RCAN1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate
Predicted Molecular Weight:
28 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store RCAN1 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
RCAN1
Additional Names:
RCAN1, ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1
Protein Accession Number:
NP_004405
Protein Gi Number:
33620725
Ncbi Gene Id Number:
1827
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.
Background Reference 1:
Riper, D.V., (2008) Arch. Biochem. Biophys. 472 (1), 43-50.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

25-434

List Size:
100 ul

List Price:

$519.00

Datasheet
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