RCBTB1 Antibody

CATALOG NUMBER: 58-739

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This RCBTB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-377 amino acids from the Central region of human RCBTB1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
58 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RCBTB1
Additional Names:
RCC1 and BTB domain-containing protein 1, Chronic lymphocytic leukemia deletion region gene 7 protein, CLL deletion region gene 7 protein, Regulator of chromosome condensation and BTB domain-containing protein 1, RCBTB1, CLLD7, E45
Protein Accession Number:
Q8NDN9
Protein Gi Number:
74751227
Ncbi Gene Id Number:
55213
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein with an N-terminal RCC1 domainand a C-terminal BTB (broad complex, tramtrack and bric-a-brac)domain. In rat, over-expression of this gene in vascular smoothmuscle cells induced cellular hypertrophy. In rat, the C-terminusof RCBTB1 interacts with the angiotensin II receptor-1A. In humans,this gene maps to a region of chromosome 13q that is frequentlydeleted in B-cell chronic lymphocytic leukemia and other lymphoidmalignancies.
Background Reference 1:
Genuneit, J., et al. Clin. Exp. Allergy 39(12):1875-1888(2009)
Background Reference 2:
Guo, D.F., et al. J. Biol. Chem. 279(20):21109-21120(2004)
Background Reference 3:
Dunham, A., et al. Nature 428(6982):522-528(2004)
Background Reference 4:
Solomou, E.E., et al. Leuk. Lymphoma 44(9):1579-1585(2003)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-739

List Size:
400 ul

List Price:

$495.00

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