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Western blot analysis of RGPD5 in human thymus tissue lysate with RGPD5 antibody at 1 μg/mL in (A) the absence and (B) the presense of blocking peptide.
Western blot analysis of RGPD5 in human thymus tissue lysate with RGPD5 antibody at 1 μg/mL in (A) the absence and (B) the presense of blocking peptide.
Trial Size

RGPD5 Antibody

CATALOG NUMBER: 4587

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
RGPD5 antibody was raised against a 23 amino acid synthetic peptide from near the center of human RGPD5.
The immunogen is located within amino acids 1130 - 1180 of RGPD5.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
RGPD5 antibody can be used for detection of RGPD5 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Positive Control 1:
Cat. No. 1314 - Human Thymus Tissue Lysate
Purification:
RGPD5 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
RGPD5 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
RGPD5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RGPD5
Additional Names:
RGPD5 Antibody: BS63, RGP5, BS-63, HEL161, RANBP2L1, RGP7, RGPD7, RGPD6, RANBP2L2, RGP6, Sperm membrane protein BS-63, RanBP2L1
Protein Accession Number:
NP_005045
Protein Gi Number:
83267877
Ncbi Gene Id Number:
84220
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
RGPD5 Antibody: The RANBP2-like and GRIP domain containing 5 protein (RGPD5) has high similarity to RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex. The gene coding for RGPD5 is thought to have arisen from a gene duplication event of RANBP2 as these highly homologous genes are located close to each other at chromosome 2q11-q12. RGPD5 was identified as an HIV dependency factor (HDF), suggesting that RGPD5 may be an important drug target in HIV treatment. At least two isoforms of RGPD5 are known to exist, of which the shorter isoform is expressed primarily in testis, while the longer of the two is expressed at low levels in a number of somatic tissues.
Background Reference 1:
Nothwang HG, Rensing C, Kubler M, et al. Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on chromosome 2q11-q12. Genomics1998; 47:383-92.
Background Reference 2:
Brass AL, Dykxhoorn DM, Benita Y, et al. Identification of host proteins required for HIV infection through a functional genomic screen. Science2008; 319:921-6.
Background Reference 3:
Wang LF, Zhu HD, Miao SY, et al. Molecular cloning and characterization of a novel testis-specific nucleoporin-related gene. Arch. Androl.1999; 42:71-84.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

4587

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

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