RGS10 Antibody

CATALOG NUMBER: 31-068

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RGS10.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
RGS10 antibody can be used for detection of RGS10 by ELISA at 1:1562500. RGS10 antibody can be used for detection of RGS10 by western blot at 0.2 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
21 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store RGS10 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
RGS10
Additional Names:
RGS10,
Protein Accession Number:
NP_001005339
Protein Gi Number:
52694755
Ncbi Gene Id Number:
6001
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
RGS10 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. It associates specifically with the activated forms of the G protein subunits G (I)-ALPHA and G (Z)- alpha but fails to interact with the structurally and functionally distinct G (S)-alpha subunit. Activity on G (Z)-alpha is inhibited by palmitoylation of the G-protein.
Background Reference 1:
Chatterjee, T.K. et al., (2000) J. Biol. Chem. 275 (31), 24013-24021.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

31-068

List Size:
100 ul

List Price:

$519.00

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