RGS11 Antibody

CATALOG NUMBER: 58-884

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This RGS11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human RGS11.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
53 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RGS11
Additional Names:
Regulator of G-protein signaling 11, RGS11, RGS11
Protein Accession Number:
O94810
Ncbi Gene Id Number:
8786
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene belongs to the RGS(regulator of G protein signaling) family. Members of the RGSfamily act as GTPase-activating proteins on the alpha subunits ofheterotrimeric, signal-transducing G proteins. This proteininhibits signal transduction by increasing the GTPase activity of Gprotein alpha subunits, thereby driving them into their inactiveGDP-bound form. Alternative splicing occurs at this locus and twotranscript variants encoding distinct isoforms have beenidentified.
Background Reference 1:
Wang, J., et al. Carcinogenesis 31(10):1755-1761(2010)
Background Reference 2:
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Background Reference 3:
Saleem, Y., et al. Biochem. Biophys. Res. Commun. 386(1):65-70(2009)
Background Reference 4:
Martin, J., et al. Nature 432(7020):988-994(2004)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-884

List Size:
400 ul

List Price:

$495.00

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