RGS11 (M-136) Antibody

CATALOG NUMBER: XW-7520

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Immunogen:
111-246
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
RGS11 (M-136) antibody can be used for the detection of RGS11 (M-136) by Western blot, may also work for IHC and ICC.
Predicted Molecular Weight:
52.9 kDa (calculated)
Purification:
Antigen affinity-purified
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
RGS11 (M-136) antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RGS11
Additional Names:
Regulator of G-protein signaling 11RGS11, RS11,
Protein Accession Number:
NP_899180.1
Protein Gi Number:
34452688
Ncbi Gene Id Number:
8786
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Regulator of G-protein signalling 11. This protein belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the α subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein α subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
Background Reference 1:
Snow,B. E., Krumins,A. M., Brothers,G. M., Lee,S. F., Wall,M. A., Chung,S., Mangion,J., Arya,S., Gilman,A. G. and Siderovski,D. P. A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits. Proc. Natl. Acad. Sci. U. S. A. 95 (22), 13307-13312 (1998).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7520

List Size:
0.05 mg

List Price:

$565.00

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