RGS5 Antibody

CATALOG NUMBER: 58-079

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This RGS5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human RGS5.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
21 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RGS5
Additional Names:
Regulator of G-protein signaling 5, RGS5, RGS5
Protein Accession Number:
O15539
Ncbi Gene Id Number:
8490
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the regulators of G proteinsignaling (RGS) family. The RGS proteins are signal transductionmolecules which are involved in the regulation of heterotrimeric Gproteins by acting as GTPase activators. This gene is ahypoxia-inducible factor-1 dependent, hypoxia-induced gene which isinvolved in the induction of endothelial apoptosis. This gene isalso one of three genes on chromosome 1q contributing to elevatedblood pressure. Alternatively spliced transcript variants encodingdifferent isoforms have been identified.
Background Reference 1:
Wang, J., et al. Carcinogenesis 31(10):1755-1761(2010)
Background Reference 2:
Li, H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(31):13818-13823(2010)
Background Reference 3:
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Background Reference 4:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-079

List Size:
400 ul

List Price:

$495.00

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