RGS8 Antibody

CATALOG NUMBER: 58-468

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This RGS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human RGS8.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
21 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RGS8
Additional Names:
Regulator of G-protein signaling 8, RGS8, RGS8
Protein Accession Number:
P57771
Protein Gi Number:
13124465
Ncbi Gene Id Number:
85397
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
RGS8 is a member of the regulator of G proteinsignaling (RGS) family and encodes a protein with a single RGSdomain. Regulator of G protein signaling (RGS) proteins areregulatory and structural components of G protein-coupled receptorcomplexes. They accelerate transit through the cycle of GTP bindingand hydrolysis to GDP, thereby terminating signal transduction, butparadoxically, also accelerate receptor-stimulated activation.
Background Reference 1:
Wang, J., et al. Carcinogenesis 31(10):1755-1761(2010)
Background Reference 2:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 3:
Fujii, S., et al. Biochem. Biophys. Res. Commun. 377(1):200-204(2008)
Background Reference 4:
Campbell, D.B., et al. Schizophr. Res. 101 (1-3), 67-75 (2008) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-468

List Size:
400 ul

List Price:

$495.00

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