RHD Antibody

CATALOG NUMBER: 59-029

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This RHD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-201 amino acids from the Central region of human RHD.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
45 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RHD
Additional Names:
Blood group Rh(D) polypeptide, RHXIII, Rh polypeptide 2, RhPII, Rhesus D antigen, CD240D, RHD
Protein Accession Number:
Q02161
Protein Gi Number:
296452980
Ncbi Gene Id Number:
6007
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The Rh blood group system is the second most clinicallysignificant of the blood groups, second only to ABO. It is also themost polymorphic of the blood groups, with variations due todeletions, gene conversions, and missense mutations. The Rh bloodgroup includes this gene, which encodes the RhD protein, and asecond gene that encodes both the RhC and RhE antigens on a singlepolypeptide. The two genes, and a third unrelated gene, are foundin a cluster on chromosome 1. The classification of Rh-positive andRh-negative individuals is determined by the presence or absence ofthe highly immunogenic RhD protein on the surface of erythrocytes.Multiple transcript variants encoding different isoforms have beenfound for this gene.
Background Reference 1:
Flegr, J., et al. Folia Parasitol. 57(2):143-150(2010)
Background Reference 2:
Liu, H.C., et al. Biochim. Biophys. Acta 1800(6):565-573(2010)
Background Reference 3:
Schmid, P., et al. Transfusion 50(1):267-269(2010)
Background Reference 4:
Wang, X.D., et al. Eur. J. Clin. Invest. 39(7):607-617(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-029

List Size:
400 ul

List Price:

$495.00

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