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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
RLN1/RLN2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

RLN1/RLN2 Antibody

CATALOG NUMBER: 57-316

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This RLN1/RLN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-165 amino acids from the C-terminal region of human RLN1/RLN2.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
21 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RLN1
Additional Names:
Prorelaxin H1, Relaxin B chain, Relaxin A chain, RLN1
Protein Accession Number:
P04808
Protein Gi Number:
132280
Ncbi Gene Id Number:
6013
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Relaxins are known endocrine and autocrine/paracrinehormones, belonging to the insulin gene superfamily. In the humanthere are three non-allelic relaxin genes, RLN1, RLN2 and RLN3.RLN1 and RLN2 share high sequence homology. This encoded protein issynthesized as a single-chain polypeptide but the active formconsists of an A chain and a B chain linked by disulfide bonds;however, their exact cleavage sites have not been described.Relaxin is produced by the ovary, and targets the mammalianreproductive system to ripen the cervix, elongate the pubicsymphysis and inhibit uterine contraction. It may have additionalroles in enhancing sperm motility, regulating blood pressure,controlling heart rate and releasing oxytocin and vasopressin. Thisgene has multiple polyadenylation sites. There are multiplealternatively spliced transcript variants described for this genebut their full length nature is not known yet. [provided byRefSeq].
Background Reference 1:
Radestock, Y., et al. Mol. Cancer Res. 8(4):494-506(2010)
Background Reference 2:
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Background Reference 3:
Ferlin, A., et al. Bone 46(2):504-513(2010)
Background Reference 4:
Vogel, I., et al. In Vivo 23(6):1005-1009(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-316

List Size:
400 ul

List Price:

$495.00

Datasheet
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