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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

RNASE1 Antibody

CATALOG NUMBER: 60-936

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This RNASE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human RNASE1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
18 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RNASE1
Additional Names:
Ribonuclease pancreatic, HP-RNase, RIB-1, RNase UpI-1, Ribonuclease 1, RNase 1, Ribonuclease A, RNase A, RNASE1, RIB1, RNS1
Protein Accession Number:
P07998
Protein Gi Number:
1350818
Ncbi Gene Id Number:
6035
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the pancreatic-type ofsecretory ribonucleases, a subset of the ribonuclease Asuperfamily. The encoded endonuclease cleaves internalphosphodiester RNA bonds on the 3'-side of pyrimidine bases. Itprefers poly(C) as a substrate and hydrolyzes 2',3'-cyclicnucleotides, with a pH optimum near 8.0. The encoded protein ismonomeric and more commonly acts to degrade ds-RNA over ss-RNA.Alternative splicing occurs at this locus and four transcriptvariants encoding the same protein have been identified. [providedby RefSeq].
Background Reference 1:
D'Alessio, G. Biopolymers 91(12):989-994(2009)
Background Reference 2:
Kover, K.E., et al. J. Mol. Biol. 379(5):953-965(2008)
Background Reference 3:
Ueki, M., et al. Biochem. Genet. 46 (3-4), 145-153 (2008) :
Background Reference 4:
Johnson, R.J., et al. Biochemistry 46(36):10308-10316(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-936

List Size:
400 ul

List Price:

$495.00

Datasheet
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