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Western blot analysis of RNASEH2B Antibody in CEM cell line lysates (35ug/lane)
RNASEH2B Antibody IHC analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis of RNASEH2B Antibody in CEM cell line lysates (35ug/lane)

RNASEH2B Antibody

CATALOG NUMBER: 61-658

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This RNASEH2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-157 amino acids from the Central region of human RNASEH2B.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Predicted Molecular Weight:
35 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RNASEH2B
Additional Names:
Ribonuclease H2 subunit B, RNase H2 subunit B, Aicardi-Goutieres syndrome 2 protein, AGS2, Deleted in lymphocytic leukemia 8, Ribonuclease HI subunit B, RNASEH2B, DLEU8
Protein Accession Number:
Q5TBB1
Protein Gi Number:
74745929
Ncbi Gene Id Number:
79621
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
RNASEH2B is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. RNASEH2B is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication.
Background Reference 1:
Crozat, K., et al. Immunol. Rev. 227(1):129-149(2009)
Background Reference 2:
Chon, H., et al. Nucleic Acids Res. 37(1):96-110(2009)
Background Reference 3:
Crow, Y.J., et al. Dev Med Child Neurol 50(6):410-416(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-658

List Size:
400 ul

List Price:

$495.00

Datasheet
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