RNF2 Antibody

CATALOG NUMBER: 28-046

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RNF2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
RNF2 antibody can be used for detection of RNF2 by ELISA at 1:312500. RNF2 antibody can be used for detection of RNF2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1224 - Daudi Cell Lysate
Predicted Molecular Weight:
38 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store RNF2 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
RNF2
Additional Names:
RNF2, BAP1, DING, BAP-1, HIPI3, RING2, RING1B
Protein Accession Number:
NP_009143
Protein Gi Number:
6005747
Ncbi Gene Id Number:
6045
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by RNF2 is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
Background Reference 1:
Voncken, J.W., et al., (2003) Proc. Natl. Acad. Sci. U.S.A. 100 (5), 2468-2473.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-046

List Size:
100 ul

List Price:

$519.00

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