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Western blot analysis in A549 cell line lysates (35ug/lane).
Western blot analysis in A549 cell line lysates (35ug/lane).

RNF6 Antibody

CATALOG NUMBER: 60-356

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This RNF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 529-558 amino acids from the C-terminal region of human RNF6.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
78 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RNF6
Additional Names:
E3 ubiquitin-protein ligase RNF6, 632-, RNF6, SPG2
Protein Accession Number:
Q9Y252
Protein Gi Number:
13124536
Ncbi Gene Id Number:
6049
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene contains a RING-H2 fingermotif. Deletions and mutations in this gene were detected inesophageal squamous cell carcinoma (ESCC), suggesting that thisprotein may be a potential tumor suppressor. Studies of the mousecounterpart suggested a role of this protein in the transcriptionregulation that controls germinal differentiation. Multiplealternatively spliced transcript variants encoding the same proteinare observed.
Background Reference 1:
Xu, K., et al. Cancer Cell 15(4):270-282(2009)
Background Reference 2:
Zhu, L., et al. Sci. China, C, Life Sci. 51(4):302-307(2008)
Background Reference 3:
Tursun, B., et al. Genes Dev. 19(19):2307-2319(2005)
Background Reference 4:
Lo, H.S., et al. Cancer Res. 62(15):4191-4193(2002)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-356

List Size:
400 ul

List Price:

$495.00

Datasheet
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