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Western blot analysis in CEM cell line lysates (35ug/lane).
Western blot analysis in CEM cell line lysates (35ug/lane).

RORC Antibody

CATALOG NUMBER: 57-272

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This RORC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human RORC.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
58 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RORC
Additional Names:
Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group F member 3, RAR-related orphan receptor C, Retinoid-related orphan receptor-gamma, RORC, NR1F3, RORG, RZRG
Protein Accession Number:
P51449
Protein Gi Number:
49066040
Ncbi Gene Id Number:
6097
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a DNA-bindingtranscription factor and is a member of the NR1 subfamily ofnuclear hormone receptors. The specific functions of this proteinare not known; however, studies of a similar gene in mice haveshown that this gene may be essential for lymphoid organogenesisand may play an important regulatory role in thymopoiesis. Inaddition, studies in mice suggest that the protein encoded by thisgene may inhibit the expression of Fas ligand and IL2. Twotranscript variants encoding different isoforms have been found forthis gene.
Background Reference 1:
Wang, Y., et al. Biochim. Biophys. Acta 1801(8):917-923(2010)
Background Reference 2:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 3:
Burgler, S., et al. J. Immunol. 184(11):6161-6169(2010)
Background Reference 4:
Jin, L., et al. Mol. Endocrinol. 24(5):923-929(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-272

List Size:
400 ul

List Price:

$495.00

Datasheet
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