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Western blot analysis in A549 cell line lysates (35ug/lane).
Western blot analysis in A549 cell line lysates (35ug/lane).

S1PR5 Antibody

CATALOG NUMBER: 57-714

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This S1PR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-247 amino acids from the Central region of human S1PR5.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
42 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
S1PR5
Additional Names:
Sphingosine 1-phosphate receptor 5, S1P receptor 5, S1P5, Endothelial differentiation G-protein-coupled receptor 8, Sphingosine 1-phosphate receptor Edg-8, S1P receptor Edg-8, S1PR5, EDG8
Protein Accession Number:
Q9H228
Protein Gi Number:
62510663
Ncbi Gene Id Number:
53637
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The lysosphingolipid sphingosine 1-phosphate (S1P)regulates cell proliferation, apoptosis, motility, and neuriteretraction. Its actions may be both intracellular as a secondmessenger and extracellular as a receptor ligand. S1P and thestructurally related lysolipid mediator lysophosphatidic acid (LPA)signal cells through a set of G protein-coupled receptors known asEDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1Preceptors; others (e.g., EDG2; MIM 602282) are LPAreceptors.
Background Reference 1:
Chang, C.L., et al. Am. J. Physiol., Cell Physiol. 297 (2), C451-C458 (2009) :
Background Reference 2:
Gillies, L., et al. Cell. Signal. 21(5):675-684(2009)
Background Reference 3:
Miron, V.E., et al. Ann. Neurol. 63(1):61-71(2008)
Background Reference 4:
Ulfig, N., et al. Acta Histochem. 106(5):373-378(2004)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-714

List Size:
400 ul

List Price:

$495.00

Datasheet
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