SAP30 Antibody

CATALOG NUMBER: 58-906

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SAP30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-218 amino acids from the C-terminal region of human SAP30.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
23 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SAP30
Additional Names:
Histone deacetylase complex subunit SAP30, 30 kDa Sin3-associated polypeptide, Sin3 corepressor complex subunit SAP30, Sin3-associated polypeptide p30, SAP30 (HGNC:10532)
Protein Accession Number:
O75446
Ncbi Gene Id Number:
8819
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Histone acetylation plays a key role in the regulation ofeukaryotic gene expression. Histone acetylation and deacetylationare catalyzed by multisubunit complexes. The protein encoded bythis gene is a component of the histone deacetylase complex, whichincludes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and otherpolypeptides. This complex is active in deacetylating core histoneoctamers, but inactive in deacetylating nucleosomal histones. Apseudogene of this gene is located on chromosome 3. [provided byRefSeq].
Background Reference 1:
Brandt, S., et al. Int. J. Biochem. Cell Biol. 42(9):1472-1481(2010)
Background Reference 2:
Viiri, K.M., et al. Mol. Cell. Biol. 29(2):342-356(2009)
Background Reference 3:
Sichtig, N., et al. Arch. Biochem. Biophys. 467(1):67-75(2007)
Background Reference 4:
Szafranski, K., et al. Genome Biol.(8), R154 (2007) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-906

List Size:
400 ul

List Price:

$495.00

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