SARS-CoV-2 (COVID-19) NSP16 Antibody

CATALOG NUMBER: 20-276

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Sheep
Species Reactivity:
Virus
Conjugate:
Unconjugated
Specifications
Host Species:
Sheep
Species Reactivity:
Virus
Immunogen:
GST-SARS-CoV2 NSP16
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Detection Antibodies: 1 μg/ml Ab, 5% BSA in TBS-T, 4°C overnight
Blocking: 5% milk in TBS-T, 1h room temp
Secondary Antibodies: 1:15,000 donkey anti-sheep, 1:15,000 donkey anti-rabbot, in TBS-T, 1h room temp
Wash: TBS-T, 4x 10 min
Purification:
Antibodies are affinity purified against the antigen and eluted with low pH.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Antibody supplied in PBS.
Concentration:
batch dependent
Storage Conditions:
Aliquot and store at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ORF1ab
Additional Names:
SARS-CoV-2-NSP16
Ncbi Gene Id Number:
43740578
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. Targeting PLpro with antiviral drugs may have an advantage in not only inhibiting viral replication but also inhibiting the dysregulation of signaling cascades in infected cells that may lead to cell death in surrounding, uninfected cells.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

20-276

List Size:
0.1 mg

List Price:

$565.00

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