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SARS-CoV-2 (COVID-19) Omicron Variant Spike RBD (His-Avi Tag) Recombinant Protein

CATALOG NUMBER: 95-128

Tested Applications:
ELISA, SDS-PAGE, WB
Specifications
source-species:
HEK293 cells
Species:
SARS-CoV-2 (COVID-19, 2019-nCoV) Spike Protein
source-species:
HEK293 cells
Recombinant Protein Sequence:
Arg319-Phe541 (G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H.)-His-Avi
Fusion Tag:
His-Avi tag at C-terminus
Tested Applications:
ELISA, SDS-PAGE, WB
Application Note:
This recombinant protein can be used for WB and ELISA. For research use only.
Predicted Molecular Weight:
35 kD
Purity:
> 95% as determined by Bis-Tris PAGE
physical-state:
Liquid
Buffer:
PBS (pH 7.4).
Storage Conditions:
Store in working aliquots at -70°C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
S
Additional Names:
S protein RBD, Spike glycoprotein Receptor-binding domain, S glycoprotein RBD, Spike protein RBD, Delta variant spike RBD
Protein Accession Number:
QHD43416.1
Ncbi Gene Id Number:
43740578
Background:
SARS-CoV-2 Omicron variant, a variant of concern (VOC), known as B.1.1.529, was detected in South Africa at the end of November in 2021. However, it rapidly spread all over of the world and now it is the dominant variant in the world, which account for more than 90% of the new cases. Omicron variant spike protein carries around 30 amino acid changes, including mutations, deletions and insertions, in which the receptor binding domain (RBD) protein contains 15 mutations. Enhanced transmission of the Omicron variant was observed globally, which is at least 70 times more contagious than the other variants. The Omicron variant affects the effectiveness of COVID-19 vaccine and is resistant to neutralization (monoclonal antibody treatments) to a large extent.
Background Reference 1:
Gowrisankar et al. European Physical Journal Plus, 2022, 137(1), 100.
Background Reference 2:
Zhang et al. PNAS of U.S.A. 2021, 118(47):e2109905118.
Background Reference 3:
Cameroni et al. Nature 2021.
Background Reference 4:
Rossler et al. NEJM 2022.
Background Reference 5:
Muik et al. Science 2022

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

95-128

List Size:
0.05 mg

List Price:

$289.00

Datasheet
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