SARS-CoV-2 (COVID-19) UK variant (B.1.1.7) Spike S1 (N501Y) Recombinant Protein

CATALOG NUMBER: 11-084

Tested Applications:
ELISA, WB
Specifications
source-species:
HEK293 cells
Species:
SARS Spike Protein
source-species:
HEK293 cells
Recombinant Protein Sequence:
Val16-Arg685 (N501Y)
Fusion Tag:
His-Avi
Tested Applications:
ELISA, WB
Application Note:
SDS-PAGE
Purity:
> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC

Endotoxin level is less than 1EU per ug by the LAL method.
physical-state:
Lyophilized
Buffer:
20mM PB (pH 7.4). 5 % trehalose is added as protectant before lyophilization.
Storage Conditions:
Store in working aliquots at -20°C. Avoid freeze/thaw cycles.
Additional Names:
S protein, Spike glycoprotein, S glycoprotein, Spike protein
Protein Accession Number:
YP_009724390.1
Background:
A new variant of SARS-CoV-2 is spreading in the UK and is rapidly becoming a global threat. It ischaracterized by multiple mutations in the spike protein. Among them, N501Y is of major concernbecause it involves one of the six key amino acid residues determining a tight interaction of theSARS-CoV-2 receptor-binding domain (RBD) with its cellular receptor angiotensin-converting enzyme2 (ACE2).

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

11-084

List Size:
0.1 mg

List Price:

$515.00

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