SART3 Antibody

CATALOG NUMBER: 29-012

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SART3.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
SART3 antibody can be used for detection of SART3 by ELISA at 1:62500. SART3 antibody can be used for detection of SART3 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
40 kDa, 110 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store SART3 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
SART3
Additional Names:
SART3, P100, p110, DSAP1, TIP110, p110(nrb), RP11-13G14
Protein Accession Number:
AAK69347
Protein Gi Number:
14579643
Ncbi Gene Id Number:
9733
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
SART3 is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. SART3 is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This protein is thought to be involved in the regulation of mRNA splicing.
Background Reference 1:
Liu, Y., (2002) J. Biol. Chem. 277 (26), 23854-23863.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

29-012

List Size:
100 ul

List Price:

$473.00

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