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46-343 (10ug/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
46-343 (10ug/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

SCN5A Antibody

CATALOG NUMBER: 46-343

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC
Host Species:
Goat
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Goat
Species Reactivity:
Human
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Cow
Immunogen:
The immunogen for this antibody is: C-ETDDQSPEKIN
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC
Application Note:
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Preliminary experiments in lysates of Human Breast and Heart tissues gave no specific signal but low background (at antibody concentration up to 1ug/ml).Immunohistochemistry:Paraffin embedded Human Brain (Cortex). Recommended concentration: 10ug/ml.
Specificity:
This antibody is expected to recognise all reported isoforms (NP_932173.1; NP_000326.2; NP_001092874.1; NP_001092875.1).
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.Aliquot and store at -20°C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Storage Conditions:
Aliquot and store at -20°C. Minimize freezing and thawing.
Ncbi Official Symbol:
SCN5A
Additional Names:
SCN5A, CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, ICCD, HH1, IVF, LQT3, SSS1, PFHB1, SSS1, sodium channel, voltage-gated, type V, alpha subunit, Nav1.5, sodium channel, voltage-gated, type V, alpha (long QT syndrome 3), cardiac sodium channel alpha subunit, sodium channel, voltage-gated, type V, alpha polypeptide (long (electrocardiographic) QT syndrome 3), VF1, cardiac tetrodotoxin-insensitive voltage-dependent sodium channel alpha subunit, sodium channel protein type V alpha subunit, voltage-gated sodium channel type V alpha
Protein Accession Number:
NP_932173.1,NP_000326.2,NP_001092874.1,NP_001092875.1,NP_001153632.1,NP_001153633.1
Protein Gi Number:
37622907
Ncbi Gene Id Number:
6331
Background Reference 1:
Olson TM, Michels VV, Ballew JD, Reyna SP, Karst ML, Herron KJ, Horton SC, Rodeheffer RJ, Anderson JL. Sodium channel mutations and susceptibility to heart failure and atrial fibrillation. JAMA. 2005 Jan 26;293(4):447-54.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

46-343

List Size:
0.1 mg

List Price:

$495.00

Datasheet
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