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Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis in K562 cell line lysates (35ug/lane).

SCN5A Antibody

CATALOG NUMBER: 60-210

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This SCN5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-70 amino acids from the N-terminal region of human SCN5A.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
227 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SCN5A
Additional Names:
Sodium channel protein type 5 subunit alpha, HH1, Sodium channel protein cardiac muscle subunit alpha, Sodium channel protein type V subunit alpha, Voltage-gated sodium channel subunit alpha Nav15, SCN5A
Protein Accession Number:
Q14524
Protein Gi Number:
215273881
Ncbi Gene Id Number:
6331
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is an integral membraneprotein and tetrodotoxin-resistant voltage-gated sodium channelsubunit. This protein is found primarily in cardiac muscle and isresponsible for the initial upstroke of the action potential in anelectrocardiogram. Defects in this gene are a cause of long QTsyndrome type 3 (LQT3), an autosomal dominant cardiac disease.Alternative splicing results in several transcript variantsencoding different isoforms.
Background Reference 1:
Liu, M., et al. Circ. Res. 107(8):967-974(2010)
Background Reference 2:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 3:
van Stuijvenberg, L., et al. DNA Cell Biol. 29(10):577-587(2010)
Background Reference 4:
House, C.D., et al. Cancer Res. 70(17):6957-6967(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-210

List Size:
400 ul

List Price:

$495.00

Datasheet
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