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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

SCNN1B Antibody

CATALOG NUMBER: 60-822

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This SCNN1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-332 amino acids from the Central region of human SCNN1B.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
73 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SCNN1B
Additional Names:
Amiloride-sensitive sodium channel subunit beta, Beta-NaCH, Epithelial Na(+) channel subunit beta, Beta-ENaC, ENaCB, Nonvoltage-gated sodium channel 1 subunit beta, SCNEB, SCNN1B
Protein Accession Number:
P51168
Protein Gi Number:
8928561
Ncbi Gene Id Number:
6338
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Nonvoltage-gated, amiloride-sensitive, sodium channelscontrol fluid and electrolyte transport across epithelia in manyorgans. These channels are heteromeric complexes consisting of 3subunits: alpha, beta, and gamma. This gene encodes the betasubunit, and mutations in this gene have been associated withpseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Song, W., et al. J. Biol. Chem. 285(13):9716-9728(2010)
Background Reference 3:
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
Background Reference 4:
McGeachie, M., et al. Circulation 120(24):2448-2454(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-822

List Size:
400 ul

List Price:

$495.00

Datasheet
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